How To Reduce Risk And Effort When Migrating A Trial Master File

By Cfyn Markwick-Day

Migrating Trial Master File (TMF) data is a relatively common occurrence, typically driven by a range of scenarios such as the adoption of a new electronic Trial Master File (eTMF) system, transferring a TMF from a Contract Research Organization (CRO) to the trial sponsor, moving the TMF from one CRO to another, asset acquisitions or divestitures by a trial sponsor, corporate mergers and acquisitions, or the consolidation of eTMF information from various sources into a central eTMF.

However, TMF data migration is not without its challenges and risks. In a recent "Ask An Expert" webinar by Phlexglobal, which can be viewed on-demand, a survey of 119 industry professionals revealed common challenges in TMF migration, notably issues related to corrupt and missing data, aligning with Phlexglobal's own experience in successfully conducting numerous TMF migrations.

In this blog, the author provides a summary of key tips, checklists, and lessons learned, aimed at mitigating the risks and efforts associated with migrating a TMF. For a more in-depth exploration of this topic, you can reference the webinar mentioned above, peruse our step-by-step guide to TMF migrations, or reach out to us with any inquiries, as our team of TMF experts is readily available to assist.